Endothelial Cell Metabolism in Atherosclerosis
نویسندگان
چکیده
منابع مشابه
Endothelial cell metabolism: parallels and divergences with cancer cell metabolism
The stromal vasculature in tumors is a vital conduit of nutrients and oxygen for cancer cells. To date, the vast majority of studies have focused on unraveling the genetic basis of vessel sprouting (also termed angiogenesis). In contrast to the widely studied changes in cancer cell metabolism, insight in the metabolic regulation of angiogenesis is only just emerging. These studies show that met...
متن کاملEndothelial progenitor cell therapy in atherosclerosis: a double-edged sword?
Atherosclerosis, an inflammatory process that selectively affects arteries, is highly prevalent in human. Thrombo-occlusive complications of atherosclerosis, including stroke and myocardial infarction, are becoming major causes of morbidity and mortality in the industrialized world. Atherosclerosis develops in response to local endothelial injuries. Endothelial dysfunction and cell loss are pro...
متن کاملMonocyte-endothelial cell interactions in the development of atherosclerosis.
The activation of endothelial cells at atherosclerotic lesion-prone sites in the arterial tree results in the up-regulation of cell adhesion molecules and chemokines, which mediate the recruitment of circulating monocytes. Accumulation of monocytes and monocyte-derived phagocytes in the wall of large arteries leads to chronic inflammation and the development and progression of atherosclerosis. ...
متن کاملRadiation-induced expression of platelet endothelial cell adhesion molecule-1 in cerebral endothelial cells
Background: Radiation-induced molecular changes on the endothelial surface of brain arteriovenous malformations (AVM) may be used as markers for specific vascular targeting agents. In this study, we examined the level of expression of platelet endothelial cell adhesion molecule-1 (PECAM-1) on brain endothelial cell surface after radiation treatment, with the aim of targeting the radiation-induc...
متن کاملAtherogenesis Treatment of atherosclerosis Thrombogenesis Endothelial cell-contraction Endothelial cell-relaxation Bleb Anti-atherosclerotic agent
school as the initial stage of human atherosclerosis, and a highly similar phenomenon was found by the author and his collaborators (1960)14) to be regularly produced as an immediate response to a single administration of atherogenic substances like cholesterol or adrenaline in rabbits and rhesus monkeys. Moreover, the authors found that such an edematous arterial response is induced by a reduc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2018
ISSN: 2296-634X
DOI: 10.3389/fcell.2018.00082